INTRAVITAL DEEP-TUMOR SINGLE-BEAM 3-PHOTON, 4-PHOTON, AND HARMONIC MICROSCOPY


Novel Stemness-Related Gene Signature Predicting Prognosis and Indicating a Different Immune Microenvironment in HNSCC

Background: The head and neck squamous cell carcinomas (HNSCC) is one of the most frequent cancers in the world, with an unfavorable prognosis.Cancer stem cells (CSCs) have been found to be responsible for HNSCC recurrence and therapeutic resistance.Methods: The stemness of HNSCC was measured using a stemness index based on mRNA expression (mRNAsi)

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Optimizing Vertical and Lateral Waveguides of kW-Class Laser Bars for Higher Peak Power, Efficiency and Lateral Beam Quality

GaAs-based, highly-efficient, kW-class, 1-cm laser bars with high peak power Popt and improved beam quality in quasi-continuous-wave mode are presented.The use of an extreme-triple-asymmetric (ETAS) epitaxial layer structure diminishes power saturation of high-power bars at high driving current.The resulting ETAS bars with 4 mm cavity Immunity prod

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